It's 1961, and to support herself and prepare for nursing school the subsequent fall, eighteen-year-old Holly Halliburton becomes a member of a very peculiar agency. They are called “The League of Bedside Sympathizers”, or at least that is their official title, though nobody seems to know what it means nor where it originated. Her job? To provide solace and smooth the transition between life and death for hospital patients who have no living or reachable kin. Having successfully undergone four separate "transitions", serious, soft-spoken Holly feels as though she is prepared for anything the agency throws her way. That is, until she is thrust to the bedside of Simon Dalaigh, a melancholy, spirited and blunt young man dying from acute Cystic Fibrosis of the lungs. Their unusual circumstances eventually throw them together into a serendipitous roadtrip--a veritable scavenger hunt across Ireland to track down Simon's roots. As their joint yearning for liberation pulls them forward, it soon becomes clear that the transition between life and death might not be as simple as they had thought.